Though Methiopropamine is a widely distributed Internet commodity, its use is not mentioned as a national crisis like that of other illicit drugs. Nevertheless, there is no current estimate of what percentage of the drug culture uses the compound. Despite being labeled legal, not much is known about its long-term physiological effects. And without FDA approval, it is wise to view Methiopropamine as merely another designer drug, of which the user risks addiction or worse.
Methiopropamine
Methiopropamine is one of the many internet-marketed chemicals sold as legal highs and has not been approved for human consumption. Known chemically as N-methyl-1-(thiophen-2-yl)propan-2-amine--the alternate is 1-(thiophen-2-yl)-2-methylaminopropane--the chemical formula is C8H13NS and its molecular weight is 155.261.
Claimed to be legal, methiopropamine is a 2-thienyl analog of the FDA approved methamphetamine compound, a Schedule II controlled substance, and wasn’t sold online until after it became public as a research chemical in the UK in December 2010. Unlike methamphetamine, methiopropamine debuted strictly as a research compound.
As such, an analytical profile of the agent was developed to assist forensic chemists who might encounter methiopropamine in case work.
Nevertheless, soon after its 2010 public arrival and despite not being ruled safe for humans, the drug grew in popularity as a legal high, for which a market quickly grew.
As such, an analytical profile of the agent was developed to assist forensic chemists who might encounter methiopropamine in case work.
Nevertheless, soon after its 2010 public arrival and despite not being ruled safe for humans, the drug grew in popularity as a legal high, for which a market quickly grew.
Large directories of suppliers in the UK offer methiopropamine for purchase, mainly because it is labeled a research chemical. Like other research compounds, users can buy methiopropamine from online brokers who use discussion forums as usage guides.
Online forums provided by brokers of the drug are good information sources, but not safe guides for methiopropamine or any other chemical ingestion.
Online forums provided by brokers of the drug are good information sources, but not safe guides for methiopropamine or any other chemical ingestion.
Users say methiopropamine induces energy, sharpens alertness, focus and enhances sexual arousal, classifying it a milder form of ecstasy. Intense hangovers are the side effects of its use, along with a loss of appetite, anxiety, increased heart rate, labored breathing, increased heart rate, chest pains and addiction.
The drug’s popularity increased over time though it is not as admired as others that mimic the effects of ecstasy, heroin or cocaine. In fact, the euphoria produced by methiopropamine is mild in comparison.
Like the above-mentioned vices, methiopropamine can be taken orally, in vaporized form or insufflated. The user reaches his peak high at three hours after ingestion, lasting for eight to eighteen hours.
Like the above-mentioned vices, methiopropamine can be taken orally, in vaporized form or insufflated. The user reaches his peak high at three hours after ingestion, lasting for eight to eighteen hours.
The negative effects of methiopropamine outweigh the positives, and for this reason, seasoned drug users do not prefer methiopropamine over other more stimulating drugs with less severe side effects. Nevertheless, this chemical compound is a widely distributed Internet commodity.
Pharmacology
The euphoric sensation happens when the flow of neurotransmitters dopamine, serotonin and norepinephrine reverses and causes neurotransmitters to flood the neuron synapses in the brain.
This is because methiopropamine functions as a selective norepinephrine-dopamine reuptake inhibitor. It resembles a serotonin reuptake inhibitor and has approximately one-third the potency of dextroamphetamine as a norepinephrine reuptake inhibitor, and one-fifth as that of dopamine.
This is because methiopropamine functions as a selective norepinephrine-dopamine reuptake inhibitor. It resembles a serotonin reuptake inhibitor and has approximately one-third the potency of dextroamphetamine as a norepinephrine reuptake inhibitor, and one-fifth as that of dopamine.
Metabolism
Methiopropamine is metabolized into active thiopropamine and thiophene S-oxides.
Similar to methamphetamine, hydroxylation, demethylation and deamination are in common; although thiophene S-oxide formation is different, as with the end product. Thiophene-2-carboxylic acid is its final metabolic form, making it hydrophilic, and therefore, easily dissolved in the body and excreted through urine. Methiopropamine is also excreted renally in its unchanged form.
Legal Issues
Methiopropamine is classified by the DEA as a designer drug though it is unscheduled at the federal level in the United States. However, independent commonwealths may still choose to prosecute. Also, it could possibly be considered an analog of methamphetamine, which is a Schedule II controlled substance.
Though methiopropamine’s structure differs from methamphetamine’s, the sale, purchase or possession of it could be eligible for prosecution under the Federal Analog Act. Some states rule the chemical compound illegal despite it being unscheduled.
Though methiopropamine’s structure differs from methamphetamine’s, the sale, purchase or possession of it could be eligible for prosecution under the Federal Analog Act. Some states rule the chemical compound illegal despite it being unscheduled.
For instance, in Florida, methiopropamine is listed as a Schedule I controlled substance. Those caught with the compound is prosecuted for possession, sale or purchase. It was added to Arizona’s “dangerous drug” list in April 2014. Methiopropamine is illegal in Finland and Germany reportedly deemed it illegal in 2013. No other classifications are documented at this time.
Researched and compiled by the blog author.
Copyright © 2014 by Peggy Hatchet James
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